What Is an Atrial Natriuretic Factor?

30-70ng / L (radioimmunoassay).

Atrial natriuretic peptide, also known as atrial natriuretic peptide or atrial peptide, is mainly synthesized, stored, and released by cardiac muscle cells, and is distributed in some peripheral tissues and organs such as the heart, pituitary, lung, and adrenal glands. Atrial natriuretic peptide also exists in the central nervous system and some peripheral ganglion cells (atrial natriuretic peptide in the central nervous system is self-synthesized and not derived from blood). Atrial natriuretic peptide can inhibit vasopressin and angiotensin, and can regulate the release of pituitary hormones and catecholamine metabolism, diuretic, sodium excretion, dilation of blood vessels, lower blood pressure, etc., is involved in water and salt metabolism Regulatory substance.
Atrial natriuretic peptide

Atrial natriuretic peptide normal value

30-70ng / L (radioimmunoassay).

Clinical Significance of Atrial Natriuretic Peptide

Decrease: seen in hyperthyroidism, atrial fibrillation, uremia after dialysis.
Elevation: seen in primary hypertension, renal insufficiency, coronary heart disease, myocardial infarction and heart failure, premature heartbeat, cirrhosis, supraventricular tachycardia, cerebral infarction, cerebral hemorrhage, primary aldosteronism, etc.

Atrial natriuretic peptides

In patients with heart failure, the atrial natriuretic peptide level is positively correlated with the severity of heart failure. The worse the cardiac function, the higher the atrial natriuretic peptide level.


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