What Is Glutathione Peroxidase?
Glutathione peroxidase (GSH-Px) is an important peroxolytic enzyme widely present in the body. The active center of GSH-Px is selenocysteine, and its activity can reflect the selenium level of the body. Selenium is a component of the GSH-Px enzyme system, which can catalyze GSH into GSSG, reduce toxic peroxides to non-toxic hydroxy compounds, thereby protecting the structure and function of cell membranes from interference and damage from peroxides. The decrease in NADPH was linearly related to the activity of glutathione peroxidase. GSH-Px mainly includes 4 types: cytosolic GSH-Px, plasma GSH-Px, phospholipid hydroperoxide GSH-Px, and gastrointestinal specific GSH-Px.
- Glutathione peroxidase (GSH-Px) is an important peroxolytic enzyme widely present in the body. GSH-Px
- It mainly includes 4 different GSH-Px, which are cytosolic GSH-Px, plasma GSH-Px, phospholipid hydroperoxide GSH-Px and gastrointestinal specific GSH-Px.
- (1) Enzyme rate method (37 ° C): 2.96 83U / g · Hb
- (2) Colorimetric method: 127.64 ± 12.68U / L
- (1) One of the indicators of the body's resistance to peroxidation;
- (2) Elevation: diabetes, sickle cell anemia, neonatal hemolysis, thalassemia;
- (3) Reduction: Keshan disease, osteoarthrosis, multiple sclerosis, cancer, coronary heart disease, chronic pancreatitis, burns, surgery;